Current Cancer and Radiation Therapy

Cancer is the number one cause of death for both men and women in Japan, and one in two people will be diagnosed with cancer during their lifetime (Ministry of Health, Labor and Welfare, Vital Statistics, 2016). Research and development of cancer treatments is one of the most important tasks facing many Doctor. "Radiation therapy" is one of the "three major cancer treatments" along with surgery and anticancer drugs. Although it has a history of more than a century, many research and development are still underway. In this article, I would like to focus on the history of radiology as well as trends in radiology being developed at Osaka Medical College.

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Cancer treatment innovation

No surgery is required, the treatment itself is completed in a short time, and there are few side effects. BNCT (Boron Neutron Capture Therapy) is expected to be an innovative cancer treatment. In June 2020, insurance coverage for BNCT began for unresectable locally advanced or locally recurrent head and neck cancer. The basis for this is the accumulation of interdisciplinary research that has been undertaken by researchers in the Kansai region since the 1980s. In order to give back the results of this series of research to more cancer patients, the Kansai BNCT Medical Center was completed in March 2018 at our university. We spoke to Koji Ono, director of the BNCT Joint Clinical Research BNCT Joint Clinical Research Institute, who has been working on research and dissemination of BNCT for over 30 years, and Keiji Nihei, Director Kansai BNCT Medical Center, who took office in 2020, about the future outlook for BNCT.

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Formulation design science

From medicines such as cold medicine and stomach medicine to various supplements and health foods, how much of the things we casually put in our mouths are absorbed by our bodies? In reality, the absorption rate of many drugs is less than 50%, and the rest is excreted from the body. The reason is that many of the active ingredients are poorly soluble in water. So, how can it be dissolved well and easily absorbed by the body? Professor Yuichi Totsuka of the Formulation Design Laboratory is working on a design that increases the absorption rate of active ingredients. If the results are applied to functional foods, they will also be useful in preventive medicine, which is important for Japan's aging population. Professor Totsuka is also using numerical simulations to predict the behavior of particles in the respiratory tract, in order to increase the effectiveness of inhaled drugs.

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Dermatology

At some point, TV weather forecasts began to provide information on UV rays. Whereas tanning used to have the image of being ``healthy'', the damage to the skin caused by ultraviolet rays is now recognized as a health risk. Exposure to ultraviolet rays can lead to skin cancer, and xeroderma pigmentosum, an incurable disease, causes severe photosensitivity symptoms and can easily develop in some people. Professor Shinichi Moriwaki of Department of Dermatology, who encountered this intractable disease during his graduate school days, saw firsthand how it was deteriorating the quality of life not only of the patients themselves but also of their families, and wanted to find a cure. Professor Moriwaki, who was also involved in creating the treatment guidelines for xeroderma pigmentosum, continues to conduct research to develop treatments, with a single-minded desire to help patients.

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Findings for giving birth and raising children safely and securely even with COVID-19

covid-19 pandemic has wreaked havoc around the world and changed the lives of many people. Pregnant women and families with children were particularly affected.
What kind of difficulties did childbirth and childcare face due to the corona crisis?
How did mothers and fathers face these obstacles?
Even during the coronavirus crisis, Osaka Medical and Pharmaceutical University has accepted many pregnant women at its university hospital. At the same time, we conducted two surveys in 2021 to clarify the changes in the childbirth and childcare environment brought about by the corona disaster and to consider future support.
In this article, I would like to introduce the survey results and advice for childcare in the future with corona era.

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Re-questioning current common sense The attitude of always thinking about the next advances medical care

In 2018, the “Kansai BNCT Medical Center” was completed at Osaka Medical and Pharmaceutical University.
What is BNCT (Boron Neutron Capture Therapy)?
It is a promising cancer treatment method that utilizes the nuclear reaction between neutrons and boron.
Aiming to improve the functionality of BNCT, we are working on the development of new boron-containing drugs.
Takashi Amano, Professor of Graduate School of Pharmaceutical Sciences.
Professor Tenman has been engaged in research on metabolic imaging since Doctoral Program at a graduate school.
I have been able to connect my research theme from molecular imaging to BNCT.
And now, as one of the few pharmaceutical researchers in the BNCT academic society, he is reviewing boron drugs from scratch and aiming to develop drugs that will become common sense for the next generation.

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Aiming to eliminate the meniscus problem, which has over 10 million potential patients

As you get older, you'll start having trouble all over your body. Knee pain is one of them, but it's not so bad that you can't walk. Feeling pain every time you move is stressful,
If left untreated, it will eventually interfere with walking.
One of the causes is damage to the meniscus, a crack or chip in the meniscus in the knee joint that causes pain every time you move.
There are only sutures or excision as treatment methods, neither of which can be said to be a fundamental treatment method.
Therefore, the meniscus injury is treated while preserving the knee as much as possible. Junior Associate Professor Shuhei Otsuki of Department of Orthopedic Surgery is working to develop such an innovative treatment method. Research using bioabsorbable materials through industry-academia collaboration is about to enter the second stage of clinical trials soon.

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I want to improve the current medical care, so I will challenge manufacturing rather than writing papers

I have a baby who was born with a heart condition. It's called a congenital heart disease, and it's a disease in which the shape of the heart and blood vessels is somehow misbuttoned.
For many years, Professor Shintaro Nemoto of Department of Thoracic and Cardiovascular Surgery has been involved in operations to save such babies, which occur in about 1 in 100 births in Japan.
However, Professor Nemoto was never satisfied with the current state of surgery. Because the baby grows and grows, the material used for the surgery does not grow. Moreover, the material deteriorates. As a result, there are many cases in which replacement is required after a few years.
What can be done to support the healthy growth of children?
What Professor Nemoto chose was to proceed with research first, then commercialize the results and bring them into the operating room.

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Bioinformatics starting now with a view to the evolution of medicine

The terms “wet” and “dry” are used in research settings.
Wet refers to the process of conducting biological experiments while handling cells in test tubes, while Dry refers to the process of analyzing experimental data using a computer.
The OMPU Dry Group is a study group voluntarily set up by students to learn computer analysis. The theme is bioinformatics, a new academic field that analyzes biological information such as DNA using computer science and elucidates life phenomena.
Participating students envision an active role in the world of medicine in the near future.

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Aiming for multidisciplinary education that is useful for team medical care in clinical settings

"Team medical care" in which medical professionals of various occupations cooperate on an equal footing in the medical field in order to respond to the Showa College of Medical Technology, where life science has developed, the Heisei era, where medical technology has made great strides, and Society 5.0, an information-driven society in the Reiwa era. The need for is increasing.
Osaka Medical College and Pharamical University has incorporated "medical and nursing fusion" into its curriculum 10 years before the establishment of the Faculty of Nursing Osaka University of Pharmaceutical Sciences scheduled for 2021, we are promoting multidisciplinary collaborative education by pharmaceutical nurses.
This time, we talked about the necessity and background of multidisciplinary education from the standpoints of pharmaceutical nurses in a round-table discussion by teachers from the Faculty of Pharmacy Faculty of Medicine, the Faculty of Nursing

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Pharmacy research that feeds back to clinical practice

The pharmacy department of a hospital is responsible for dispensing and formulating operations, drug management, and medication guidance. Generally not a "research" institution. However, the Department of Pharmacy at Osaka Medical College Hospital, under the initiative of Research & Development Center Osaka Medical College, has collaborated with medical and research institutions such as Osaka University of Pharmaceutical Sciences of Pharmaceutical Sciences and Osaka Otani University to conduct a joint research project called "Basic and Clinical Data Analysis." Research on Pharmacokinetics Analysis and Evaluation of Drug Safety". Research on a variety of themes is being conducted from a perspective unique to hospital pharmacists who continue to work in clinical settings on a daily basis. In this article, I would like to introduce the form of translational research surrounding the pharmacy department of Osaka Medical College College Hospital, taking up the characteristic research themes from this project.

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Meeting to learn advanced research in different fields

Cardiovascular surgery, physiology, Physiology, Biology, ophthalmology, Anatomy and Cell Biology... researchers with seemingly completely different specialties jump out of the university and gather at a knowledge salon in Umeda, Osaka. What they have in common is their intellectual curiosity as a medical researcher and being a university professor involved in medical education. “We need to have a sense of balance so that research and exchanges are not confined to our own area,” says Dr. Sachiko Kankichi (Department of Thoracic and Cardiovascular Surgery), the founder of the project. I followed the meeting.

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Breast Cancer Treatment and Nursing

Breast cancer is the number one cause of cancer among women. Among cancers, breast cancer surgery can be performed in a short period of time, and the prognosis is relatively good. The 5-year relative survival rate for all cancers is 65.8%, while breast cancer reaches 92.7%. However, breast cancer treatment continues for a span of 5 to 10 years to prevent recurrence and metastasis. There is also the risk of "recurrence", and we must always face related symptoms such as "lymphedema". What role does nursing play in long-term cancer treatment and daily life?

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Current Cancer and Radiation Therapy

Cancer is the number one cause of death for both men and women in Japan, and one in two people will be diagnosed with cancer during their lifetime (Ministry of Health, Labor and Welfare, Vital Statistics, 2016). Research and development of cancer treatments is one of the most important tasks facing many Doctor. "Radiation therapy" is one of the "three major cancer treatments" along with surgery and anticancer drugs. Although it has a history of more than a century, many research and development are still underway. In this article, I would like to focus on the history of radiology as well as trends in radiology being developed at Osaka Medical College.

Read the article

Cancer treatment innovation

No surgery is required, the treatment itself is completed in a short time, and there are few side effects. BNCT (Boron Neutron Capture Therapy) is expected to be an innovative cancer treatment. In June 2020, insurance coverage for BNCT began for unresectable locally advanced or locally recurrent head and neck cancer. The basis for this is the accumulation of interdisciplinary research that has been undertaken by researchers in the Kansai region since the 1980s. In order to give back the results of this series of research to more cancer patients, the Kansai BNCT Medical Center was completed in March 2018 at our university. We spoke to Koji Ono, director of the BNCT Joint Clinical Research BNCT Joint Clinical Research Institute, who has been working on research and dissemination of BNCT for over 30 years, and Keiji Nihei, Director Kansai BNCT Medical Center, who took office in 2020, about the future outlook for BNCT.

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Revolutionary cancer treatment

BNCT
(Boron neutron capture therapy)

Our university is the only academic institution in Japan with a BNCT facility, and Kansai BNCT Medical Center and BNCT Joint Clinical Research Institute conduct not only clinical practice, but also research to advance BNCT and develop specialized human resources.
We also hold the "BNCT Study Group" to promote research by researchers from multiple fields.

Creation of joint research that transcends the boundaries of specialized fields of medicine, engineering, and medicine

Kansai University/ Osaka Medical and Pharmaceutical University
Medical, Pharmaceutical and Engineering Sciences Education and Research Organization

Since its establishment in 2009, Medical, Pharmaceutical and Engineering Sciences Education and Research Organization has been promoting its business with a focus on educational programs.
Based on the activities of the past 10 years, a new research department will be established in April 2019 at the Institute Medical, Pharmaceutical and Engineering Sciences Education and Research, and will carry out activities to realize closer and deeper inter-university collaboration in the promotion of research. doing.
We believe that through research exchange activities involving students and Graduate Student, we can create joint research with an awareness of collaboration in new medical and medical industry fields.

Research content and introduction of researchers

To all companies

Would you like to create innovation for society together with Osaka Medical and Pharmaceutical University

We would like to promote research that will be needed in the future, beyond the boundaries inside and outside the university.
Please contact us if you are interested in industry-government-academia collaboration.

Research activities are summarized in "Research Seeds & Needs Collection". Please use all means.

Research related information

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