Director’s Career & Key Articles
Profile / Yasuhito Fujisaka
Major Research Area, Professional Specialty
Medical Oncology and Thoracic oncology
Phase I trial for new cancer drug focused on
molecular-target-medicine / Immune-checkpoint-inhibitor
Major Achievements of Clinical Trials as a Principal Investigator
Phase I trial for new developmental drug for solid tumor
Phase II III global trials for lung cancer
Academic Background
PhD 2008 Osaka Medical College
MD 1998 Osaka Medical College (Medical License NO.398060)
Professional Experience
Professor / Clinical Research Center, Osaka Medical College Hospital, Japan, 2020-
Director / Clinical Research Center, Osaka Medical College Hospital, Japan, 2013-present
Director / Clinical Trial Center, Osaka Medical College Hospital, Japan, 2013-2013
Associate Professor / Department of Respiratory Medicine, Osaka Medical College, 2005-present
Head Doctor / Department of Respiratory Medicine and Thoracic Oncology,
Osaka Medical College Hospital, 2016-pesent
Assistant Professor / Department of Medical Oncology, Kindai University, 2009-2012
Assistant Professor / Respiratory Medicine, Osaka Medical College Hospital, 2005-2009
Fellow / National Cancer Center Hospital, Japan, 2000-2005
Membership
Japanese Society of Medical Oncology / Fellow, Specialty Doctor, Supervisory Doctor
American Society of Clinical Oncology / Active Member
International Association for the Study of Lung Cancer / Active Member
Key Articles
| Lenvatinib in patients with advanced or metastatic thymic carcinoma (REMORA) : a multicentre, phase 2 trial |
|
| Authors | Journal |
| Jun Sato, Miyako Satouchi, Shoichi Itoh, Yusuke Okuma, Seiji Niho, Hidenori Mizugaki, Haruyasu Murakami, Yasuhito Fujisaka, Toshiyuki Kozuki, Kenichi Nakamura, Yukari Nagasaka, Mamiko Kawasaki, Tomoaki Yamada, Ryunosuke Machida, Aya Kuchiba, Yuichiro Ohe, Noboru Yamamoto |
The Lancet. Oncology 21(6) 843 - 850 June, 2020 |
| Exacerbation of autoimmune myocarditis by an immune checkpoint inhibitor is dependent on its time of administration in mice |
|
| Authors | Journal |
| Kenjiro Tsuruoka, Shigeo Wakabayashi, Hirofumi Morihara, Ninso Matsunaga, Yasuhito Fujisaka, Isao Goto, Akihisa Imagawa, Michio Asahi |
International journal of cardiology 13th April, 2020 |
| Exploration of germline variants responsible for adverse events of crizotinib in anaplastic lymphoma kinase-positive non-small cell lung cancer by target-gene panel sequencing |
|
| Authors | Journal |
| Hidenori Mizugaki, Akinobu Hamada, Tatsuhiro Shibata, Fumie Hosoda, Hiromi Nakamura, Yusuke Okuma, Takehito Shukuya, Shigeki Umemura, Atsushi Horiike, Tomoya Fukui, Yoshihito Kogure, Haruko Daga, Yoshiko Urata, Kazuhiko Yamada, Sho Saeki, Yasuhito Fujisaka, Yukiko Nakamura, Mitsuo Sato, Tatsuya Yoshida, Takamasa Hotta, Satoshi Oizumi, Yasuhiro Fujiwara, Yuichiro Ohe, Yutaka Fujiwara |
Lung cancer (Amsterdam, Netherlands) 128 20 - 25 February, 2020 |
| An early clinical trial of Salirasib, an oral RAS inhibitor, in Japanese patients with relapsed/refractory solid tumors |
|
| Authors | Journal |
| Junji Furuse, Takayasu Kurata, Naohiro Okano, Yasuhito Fujisaka, Daisuke Naruge, Toshio Shimizu, Hiroshi Kitamura, Tsutomu Iwasa, Fumio Nagashima, Kazuhiko Nakagawa |
Cancer chemotherapy and pharmacology 82(3) 511 - 519 September, 2018 |
| Phase 3 study of ceritinib vs chemotherapy in ALK-rearranged NSCLC patients previously treated with chemotherapy and crizotinib (ASCEND-5): Japanese subset |
|
| Authors | Journal |
| Katsuyuki Kiura, Fumio Imamura, Hiroshi Kagamu, Shingo Matsumoto, Toyoaki Hida, Kazuhiko Nakagawa, Miyako Satouchi, Isamu Okamoto, Mitsuhiro Takenoyama, Yasuhito Fujisaka, Takayasu Kurata, Masayuki Ito, Kota Tokushige, Ben Hatano, Makoto Nishio |
Japanese journal of clinical oncology 48(4) 367 - 375 1st April, 2020 |
| Retrospective Study of Treatment for Postoperative Local Recurrence of Lung Cancer | |
| Authors | Journal |
| Kenjiro Tsuruoka, Keiji Miyoshi, Ninso Matsunaga, Takahiko Nakamura, Shuhei Yoshida, Yousuke Tamura, Masafumi Imanishi, Soichiro Ikeda, Yasuhito Fujisaka, Isao Goto |
JOURNAL OF THORACIC ONCOLOGY 12(1) S682 - S682 January, 2017 |
| A Retrospective Analysis of the Chemotherapy for 'Very Old' Patients Aged 80 Years and Order with Advanced Lung Cancer |
|
| Authors | Journal |
| Yosuke Tamura, Yasuhito Fujisaka, Keiji Miyoshi, Ninso Matsunaga, Kenjiro Tsuruoka, Takahiko Nakamura, Shuhei Yoshida, Tetsufumi Kawaguchi, Masafumi Imanishi, Soichiro Ikeda, Isao Goto |
JOURNAL OF THORACIC ONCOLOGY 12(1) S914 - S915 January, 2017 |
| Phase I/II study of nab-paclitaxel (nab-P) with cisplatin (C) and thoracic radiation (TRT) in patients with locally advanced NSCLC: Safety results of phase I part |
|
| Authors | Journal |
| Hidetoshi Hayashi, Masakazu Ogura, Takashi Niwa, Satoshi Ikeo, Takashi Yokoi, Yoshitaro Torii, Kunio Okamoto, Yosuke Tamura, Kaoru Tanaka, Yasuhito Fujisaka, Isao Goto, Hiroyasu Kaneda, Takayasu Kurata, Hiroshige Yoshioka, Kazuhiko Nakagawa |
JOURNAL OF CLINICAL ONCOLOGY 34(15) May,2016 |
| Small-cell Lung Cancer in a Young Adult Nonsmoking Patient with Ectopic Adrenocorticotropin (ACTH) Production |
|
| Authors | Journal |
| Masahiko Aoki, Yasuhito Fujisaka, Satoshi Tokioka, Ai Hirai, Yujiro Henmi, Yosuke Inoue, Ken Narabayashi, Takeshi Yamano, Yosuke Tamura, Yutaro Egashira, Kazuhide Higuchi |
Internal medicine (Tokyo, Japan) 55(10) 1337 -9 2016 |
| A Retrospective Analysis of Adjuvant Chemotherapy in Patients with Completely Resected SCLC |
|
| Authors | Journal |
| Yosuke Tamura, Yasuhito Fujisaka, Takahito Nakamura, Hiroyuki Tsuji, Ninso Matsunaga, Tetsufumi Kawaguchi, Masashi Imanishi, Syuhei Yoshida, Keiji Miyoshi, Soichiro Ikeda, Isao Goto, Toshiaki Hanafusa |
JOURNAL OF THORACIC ONCOLOGY 10(9) S744 - S744 September, 2015 |
| Large cell neuroendocrine carcinoma of the lung withcancer-associated retinopathy | |
| Authors | Journal |
| Takahiko Nakamura, Yasuhito Fujisaka, Yosuke Tamura, Hiroyuki Tsuji, Ninso Matsunaga, Shuhei Yoshida, Masafumi Imanishi, Kazuhiko Fujita, Soichiro Ikeda, Hidehiro Oku, Isao Goto, Tsunehiko Ikeda, Toshiaki Hanafusa |
Case Reports in Oncology 8(1) 153 - 158 22 May, 2015 |
| Phase I study of amatuximab, a novel monoclonal antibody to mesothelin, in Japanese patients with advanced solid tumors |
|
| Authors | Journal |
| Yasuhito Fujisaka, Takayasu Kurata, Kaoru Tanaka, Toshihiro Kudo, Kunio Okamoto, Junji Tsurutani, Hiroyasu Kaneda, Isamu Okamoto, Masayuki Namiki, Chifumi Kitamura, Kazuhiko Nakagawa | Investigational new drugs 33(2) 380 - 8 April, 2015 |