T (Primary
Tumor) TX Primary tumor cannot be assessed, or tumor proven by the presence of malignant cells in sputum or bronchial washings but not visualized by imaging or bronchoscopy T0 No evidence of primary tumor Tis Carcinoma in situ T1 Tumor <=3 cm in greatest dimension, surrounded by lung orvisceral pleura, without bronchoscopic evidence of invasion more proximal than the lobar bronchus (i.e., not in the main bronchus) T1a Tumor <=2 cm in greatest dimension T1b Tumor >2 cm but <=3 cm in greatest dimension T2 Tumor >3 cm but <=7 cm or tumor with any of the following features (T2 tumors with these features are classified T2a if <=5 cm) Involves main bronchus, >=2 cm distal to the carina Invades visceral pleura Associated with atelectasis or obstructive pneumonitis that extends to the hilar region but does not involve the entire lung T2a Tumor >3 cm but <=5 cm in greatest dimension T2b Tumor >5 cm but <=7 cm in greatest dimension T3 Tumor >7 cm or one that directly invades any of the following: chest wall (including superior sulcus tumors), diaphragm, phrenic nerve, mediastinal pleura, parietal pericardium; or tumor in the main bronchus <2 cm distal to the carinaa but without involvement of the carina; or associated atelectasis or obstructive pneumonitis of the entire lung or separate tumor nodule(s) in the same lobe T4 Tumor of any size that invades any of the following: mediastinum, heart, great vessels, trachea, recurrent laryngeal nerve, esophagus, vertebral body, carina; separate tumor nodule(s) in a different ipsilateral lobe |
N (Regional Lymph Nodes) NX Regional lymph nodes cannot be assessed N0 No regional lymph node metastasis N1 Metastasis in ipsilateral peribronchial and/or ipsilateral hilar lymph nodes and intrapulmonary nodes, including involvement by direct extension N2 Metastasis in ipsilateral mediastinal and/or subcarinal lymph node(s) N3 Metastasis in contralateral mediastinal, contralateral hilar, ipsilateral or contralateral scalene, or supraclavicular lymph node(s) |
M (Distant Metastasis) MX Distant metastasis cannot be assessed M0 No distant metastasis M1 Distant metastasis M1a Separate tumor nodule(s) in a contralateral lobe; tumor with pleural nodules or malignant pleural (or pericardial) effusionb M1b Distant metastasis |
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6th Ed T/M Descriptor |
Proposed T/M |
N0 |
N1 |
N2 |
N3 |
T1(<=2cm) |
T1a |
IA |
IIA |
IIIA |
IIIB |
T1(>2-3cm) |
T1b |
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T2(<=5cm) |
T2a |
IB |
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T2(>5-7cm) |
T2b |
IIA |
IIB |
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T2(>7cm) |
T3 |
IIB |
IIIA |
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T3 invasion |
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T4(same lobe nodules) |
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T4(extension) |
T4 |
IIIA |
IIIB |
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M1(ipsilateral lung) |
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T4(pleural effusion) |
M1a |
IV |
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M1(contralateral lung) |
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M1(distant) |
M1b |
IV |